Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 13/20 | 0.63 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.60 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | USP2 | O75604 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | ESR1 | P03372 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | ALPL | P05186 | 1/20 | 0.58 |
| ▸ | ALPI | P09923 | 1/20 | 0.58 |
| ▸ | ALPG | P10696 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19254292 | 0.95 | CSNK2A1 (0.67) | CSNK2A1CSNK2A2CSNK2BKDM4EUSP2 | |
| SCHEMBL19254310 | 0.92 | CSNK2A1 (0.72) | CSNK2A1CSNK2A2CSNK2BKDM4EUSP2 | |
| SCHEMBL19254651 | 0.92 | CSNK2A1 (0.64) | CSNK2A1CSNK2A2CSNK2BKDM4EUSP2 | |
| SCHEMBL19207411 | 0.91 | CSNK2A1 (0.65) | CSNK2A1CSNK2A2CSNK2BKDM4EUSP2 | |
| SCHEMBL19254358 | 0.91 | CSNK2A1 (0.62) | CSNK2A1CSNK2A2CSNK2BKDM4EUSP2 | |
| SCHEMBL19254303 | 0.90 | CSNK2A1 (0.61) | CSNK2A1CSNK2A2CSNK2BKDM4EUSP2 | |
| SCHEMBL22400129 | 0.90 | CSNK2A1 (0.79) | CSNK2A1CSNK2A2CSNK2BKDM4EUSP2 | |
| SCHEMBL22400143 | 0.90 | HSD17B10 (0.74) | CSNK2A1CSNK2A2CSNK2BKDM4EUSP2 | |
| SCHEMBL19254316 | 0.89 | CSNK2A1 (0.61) | CSNK2A1CSNK2A2CSNK2BKDM4EUSP2 | |
| SCHEMBL19254356 | 0.88 | CSNK2A1 (0.59) | CSNK2A1CSNK2A2CSNK2BKDM4EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017136689-A1 | PURINE COMPOUNDS POSSESSING ANTICANCER ACTIVITY | ACADEMIA SINICA (TW) | 2017-08-10 | — | — | WO | disclosed |