Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 2/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11349031 | 1.00 | PRCP (0.56) | PRCPCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL185756 | 0.80 | PRCP (0.42) | PRCPCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL8366931 | 0.79 | CHRM2 (0.59) | CHRM2CHRM4CHRM1CHRM3NOTUM | |
| SCHEMBL11592688 | 0.78 | PRCP (0.40) | PRCPCHRM2CHRM4CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL5367455 | 0.77 | CHRM2 (0.57) | CHRM2CHRM4CHRM1CHRM3NOTUM | |
| SCHEMBL11995384 | 0.76 | CHRM2 (0.52) | CHRM2CHRM4CHRM1CHRM3NOTUM | |
| SCHEMBL2632947 | 0.76 | CHRM2 (0.52) | CHRM2CHRM4CHRM1CHRM3NOTUM | |
| SCHEMBL11346041 | 0.75 | CHRM2 (0.55) | CHRM2CHRM4CHRM1CHRM3NOTUM | |
| SCHEMBL16685211 | 0.75 | CHRM2 (0.51) | CHRM2CHRM4CHRM1CHRM3NOTUM | |
| SCHEMBL21705292 | 0.75 | CHRM2 (0.51) | CHRM2CHRM4CHRM1CHRM3NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3205650-A1 | EGFR INHIBITOR, AND PREPARATION AND APPLICATION THEREOF | Shanghai Hansoh Biomedical Co., Ltd. (CN) | 2017-08-16 | — | — | EP | disclosed |