Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 2/20 | 0.36 |
| ▸ | ATR | Q13535 | 7/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19204845 | 0.86 | CYP4F2 (0.36) | CYP4F2CYP4A11GAARETATR | |
| SCHEMBL19250505 | 0.84 | CYP4F2 (0.41) | CYP4F2CYP4A11GAARETATR | |
| SCHEMBL24012792 | 0.82 | CYP4F2 (0.50) | CYP4F2CYP4A11GAARETATR | |
| SCHEMBL19250534 | 0.82 | PDE7A (0.39) | ESR1PDE7A | |
| SCHEMBL13812030 | 0.79 | GAA (0.39) | CYP4F2CYP4A11GAARETATR | |
| SCHEMBL18371142 | 0.78 | CYP4F2 (0.39) | CYP4F2CYP4A11GAARETATR | |
| SCHEMBL19249997 | 0.77 | CYP4F2 (0.44) | CYP4F2CYP4A11GAARETATR | |
| SCHEMBL19249525 | 0.77 | ESR1 (0.42) | CYP4F2CYP4A11GAARETATR | |
| SCHEMBL18260874 | 0.75 | CYP4F2 (0.34) | CYP4F2CYP4A11ATR | |
| SCHEMBL19204872 | 0.73 | CYP4F2 (0.40) | CYP4F2CYP4A11GAARETATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133670-A1 | PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATMENT, AMELIORATION OR PREVENTION OF INFLUENZA | SAVIRA PHARMACEUTICALS GMBH (AT) | 2017-08-10 | — | — | WO | disclosed |