Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | RAB9A | P51151 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.61 |
| ▸ | RELA | Q04206 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | CA12 | O43570 | 2/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
| ▸ | CA9 | Q16790 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | BRD4 | O60885 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19272225 | 0.83 | MAPT (0.85) | MAPTRAB9ASMN1; SMN2NPC1HPGD | |
| SCHEMBL11648995 | 0.83 | MAPT (0.85) | MAPTRAB9ASMN1; SMN2NPC1HPGD | |
| SCHEMBL11649000 | 0.83 | MAPT (0.85) | MAPTRAB9ASMN1; SMN2NPC1HPGD | |
| SCHEMBL861674 | 0.82 | SMN1; SMN2 (0.84) | MAPTRAB9ASMN1; SMN2NPC1HPGD | |
| SCHEMBL13709015 | 0.81 | RXFP1 (0.57) | MAPTRAB9ASMN1; SMN2NPC1HPGD | |
| SCHEMBL14362732 | 0.81 | MAPT (0.57) | MAPTRAB9ASMN1; SMN2NPC1HPGD | |
| SCHEMBL8778393 | 0.81 | MAPT (0.63) | MAPTRAB9ASMN1; SMN2NPC1HPGD | |
| SCHEMBL12305591 | 0.80 | SMN1; SMN2 (0.58) | MAPTRAB9ASMN1; SMN2NPC1HPGD | |
| SCHEMBL21334292 | 0.79 | MAPT (0.61) | MAPTRAB9ASMN1; SMN2NPC1HPGD | |
| SCHEMBL3900564 | 0.79 | MAPT (0.61) | MAPTRAB9ASMN1; SMN2NPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10301430-B2 | Bis(azobenzene) diamines and photomechanical polymers made therefrom | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2019-05-28 | — | — | US | disclosed |
| US-9896545-B2 | Bis(azobenzene) diamines and photomechanical polymers made therefrom | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2018-02-20 | — | — | US | disclosed |
| US-20180022872-A1 | BIS(AZOBENZENE) DIAMINES AND PHOTOMECHANICAL POLYMERS MADE THEREFROM | GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2018-01-25 | — | — | US | disclosed |
| US-20170233529-A1 | BIS(AZOBENZENE) DIAMINES AND PHOTOMECHANICAL POLYMERS MADE THEREFROM | GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2017-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10301430-B2 | Bis(azobenzene) diamines and photomechanical polymers made therefrom | WASF2, PBRM1, WEE1 | MAPT 391/4885RAB9A 4397/4885SMN1; SMN2 4243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.