SCHEMBL1925571

SCHEMBL1925571

C=CCCCCOc1ccc(C(=O)Oc2ccc(CCCCC)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 5/20 0.57
NPC1 O15118 3/20 0.57
LMNA P02545 3/20 0.57
CYP1A2 P05177 1/20 0.57
CYP3A4 P08684 1/20 0.57
CYP2D6 P10635 1/20 0.57
CYP2C9 P11712 1/20 0.57
CYP2C19 P33261 1/20 0.57
SMN1; SMN2 Q16637 4/20 0.56
NFKB1 P19838 3/20 0.56
NFKB2 Q00653 3/20 0.56
RELA Q04206 3/20 0.56
MAPT P10636 4/20 0.52
PRSS1 P07477 1/20 0.51
ACR P10323 1/20 0.51
THRA P10827 4/20 0.50
KMT2A Q03164 3/20 0.50
ALDH1A1 P00352 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
POLB P06746 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8913503 0.99 NPC1 (0.58) THRBNPC1LMNACYP1A2CYP3A4
SCHEMBL9878702 0.97 MAPT (0.54) THRBNPC1LMNACYP1A2CYP3A4
SCHEMBL9879296 0.96 SMN1; SMN2 (0.55) THRBNPC1LMNACYP1A2CYP3A4
SCHEMBL9878487 0.96 SMN1; SMN2 (0.55) THRBNPC1LMNACYP1A2CYP3A4
SCHEMBL9878365 0.96 SMN1; SMN2 (0.55) THRBNPC1LMNACYP1A2CYP3A4
SCHEMBL9878004 0.96 SMN1; SMN2 (0.55) THRBNPC1LMNACYP1A2CYP3A4
SCHEMBL9878015 0.96 SMN1; SMN2 (0.55) THRBNPC1LMNACYP1A2CYP3A4
SCHEMBL9878280 0.96 SMN1; SMN2 (0.55) THRBNPC1LMNACYP1A2CYP3A4
SCHEMBL9879253 0.96 SMN1; SMN2 (0.55) THRBNPC1LMNACYP1A2CYP3A4
SCHEMBL9879063 0.96 SMN1; SMN2 (0.55) THRBNPC1LMNACYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106701106-B Alignment mechanism for optical dyes 光学转变公司 2022-03-29 CN disclosed
EP-2358845-B1 ALIGNMENT FACILITIES FOR OPTICAL DYES TRANSITIONS OPTICAL INC (US) 2014-11-12 EP disclosed
US-8828507-B2 Alignment facilities for optical dyes TRANSITIONS OPTICAL, INC. (US) 2014-09-09 US disclosed
EP-2358845-A1 ALIGNMENT FACILITIES FOR OPTICAL DYES TRANSITIONS OPTICAL, INC. (US) 2011-08-24 EP disclosed
US-8003005-B2 Alignment facilities for optical dyes TRANSITIONS OPTICAL, INC. (US) 2011-08-23 US disclosed
US-20110128457-A1 ALIGNMENT FACILITIES FOR OPTICAL DYES TRANSITIONS OPTICAL, INC. (US) 2011-06-02 US disclosed
WO-2010065406-A1 ALIGNMENT FACILITIES FOR OPTICAL DYES TRANSITIONS OPTICAL, INC. (US) 2010-06-10 WO disclosed
US-20090146104-A1 ALIGNMENT FACILITIES FOR OPTICAL DYES TRANSITIONS OPTICAL, INC. (US) 2009-06-11 US disclosed