SCHEMBL19256478

SCHEMBL19256478

Cc1ccc(Br)c(C(=O)N2CC(F)(F)C[C@@H](C)C2CNc2ncc(Cl)cn2)n1

nearest known ligand 0.77

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HCRTR1 O43613 20/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19207064 1.00 HCRTR1 (0.77) HCRTR1
SCHEMBL19207046 0.90 HCRTR1 (0.77) HCRTR1
SCHEMBL19256153 0.87 HCRTR1 (1.00) HCRTR1
SCHEMBL19256293 0.87 HCRTR1 (1.00) HCRTR1
SCHEMBL19207176 0.87 HCRTR1 (1.00) HCRTR1
SCHEMBL24381503 0.87 HCRTR1 (1.00) HCRTR1
SCHEMBL24381377 0.87 HCRTR1 (1.00) HCRTR1
SCHEMBL23639309 0.87 HCRTR1 (1.00) HCRTR1
SCHEMBL24381052 0.87 HCRTR1 (1.00) HCRTR1
SCHEMBL19256319 0.87 HCRTR1 (1.00) HCRTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017139603-A1 HALO-SUBSTITUTED PIPERIDINES AS OREXIN RECEPTOR MODULATORS ASTRAZENECA AB (SE) 2017-08-17 WO disclosed