Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
| ▸ | PRKCG | P05129 | 1/20 | 0.41 |
| ▸ | PRKCB | P05771 | 1/20 | 0.41 |
| ▸ | PRKCA | P17252 | 1/20 | 0.41 |
| ▸ | PRKCH | P24723 | 1/20 | 0.41 |
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.41 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.41 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.41 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL323637 | 1.00 | ACE2 (0.54) | ACE2OPRM1LMNATSHRCA1 | |
| SCHEMBL652603 | 0.97 | ACE2 (0.58) | ACE2OPRM1LMNATSHRSPHK1 | |
| SCHEMBL19058823 | 0.97 | ACE2 (0.58) | ACE2OPRM1LMNATSHRSPHK1 | |
| SCHEMBL3407397 | 0.97 | ACE2 (0.58) | ACE2OPRM1LMNATSHRSPHK1 | |
| SCHEMBL450698 | 0.97 | ACE2 (0.58) | ACE2OPRM1LMNATSHRSPHK1 | |
| SCHEMBL14484285 | 0.97 | ACE2 (0.58) | ACE2OPRM1LMNATSHRSPHK1 | |
| SCHEMBL650705 | 0.97 | ACE2 (0.58) | ACE2OPRM1LMNATSHRSPHK1 | |
| SCHEMBL872663 | 0.97 | ACE2 (0.58) | ACE2OPRM1LMNATSHRSPHK1 | |
| SCHEMBL3469393 | 0.97 | ACE2 (0.58) | ACE2OPRM1LMNATSHRSPHK1 | |
| SCHEMBL181032 | 0.97 | ACE2 (0.58) | ACE2OPRM1LMNATSHRSPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133630-A1 | INHIBITOR OF BRUTON'S TYROSINE KINASE | 北京盛诺基医药科技有限公司 | 2017-08-10 | — | — | WO | disclosed |