SCHEMBL19257007

SCHEMBL19257007

CC(C)(C)[Si](C)(C)c1ccc(I)cc1

nearest known ligand 0.50

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.50
NR1H3 Q13133 1/20 0.50
HDAC8 Q9BY41 1/20 0.32
APP P05067 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19256277 0.79 NR1H2 (0.54) NR1H2NR1H3
SCHEMBL988411 0.77 NR1H2 (0.52) NR1H2NR1H3
SCHEMBL18913902 0.75 NR1H2 (0.50) NR1H2NR1H3
SCHEMBL196876 0.75 NR1H2 (0.50) NR1H2NR1H3
SCHEMBL12488594 0.75 NR1H2 (0.50) NR1H2NR1H3
SCHEMBL988384 0.74 NR1H2 (0.48) NR1H2NR1H3
SCHEMBL6512153 0.73 NR1H2 (0.41) NR1H2NR1H3HDAC8APP
SCHEMBL9968169 0.73 ESR1 (0.44) NR1H2NR1H3HDAC8APP
SCHEMBL19257000 0.71 NR1H2 (0.47) NR1H2NR1H3
SCHEMBL21271550 0.71 NR1H2 (0.47) NR1H2NR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2738797-B1 ADHESIVE LAMINATE FOR TEMPORARILY ADHERING A WAFER TO A SUPPORT, WAFER PROCESSING LAMINATE CONSISTING OF SAID SUPPORT, ADHESIVE LAMINATE AND WAFER, WAFER PROCESSING MEMBER CONSISTING OF SAID SUPPORT AND SAID ADHESIVE LAMINATE, AND METHOD OF MANUFACTURING A THIN WAFER USING SAID ADHESIVE LAMINATE SHINETSU CHEMICAL CO (JP) 2017-08-16 EP disclosed