Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYBB | P04839 | 20/20 | 0.76 |
| ▸ | NOX5 | Q96PH1 | 20/20 | 0.76 |
| ▸ | NOX4 | Q9NPH5 | 20/20 | 0.76 |
| ▸ | NOX1 | Q9Y5S8 | 20/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1459191 | 0.86 | CYBB (1.00) | CYBBNOX5NOX4NOX1 | |
| SCHEMBL31291710 | 0.86 | CYBB (1.00) | CYBBNOX5NOX4NOX1 | |
| SCHEMBL1566689 | 0.86 | CYBB (1.00) | CYBBNOX5NOX4NOX1 | |
| SCHEMBL1566481 | 0.85 | CYBB (1.00) | CYBBNOX5NOX4NOX1 | |
| SCHEMBL1566290 | 0.84 | CYBB (0.74) | CYBBNOX5NOX4NOX1 | |
| SCHEMBL1565877 | 0.84 | CYBB (1.00) | CYBBNOX5NOX4NOX1 | |
| SCHEMBL1566438 | 0.82 | CYBB (1.00) | CYBBNOX5NOX4NOX1 | |
| SCHEMBL1566376 | 0.82 | CYBB (1.00) | CYBBNOX5NOX4NOX1 | |
| SCHEMBL1566482 | 0.81 | CYBB (1.00) | CYBBNOX5NOX4NOX1 | |
| SCHEMBL1565930 | 0.81 | CYBB (1.00) | CYBBNOX5NOX4NOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2483271-B1 | PYRAZOLINE DIONE DERIVATIVES AS NADPH OXIDASE INHIBITORS | GENKYOTEX SUISSE SA (CH) | 2017-08-16 | — | — | EP | disclosed |