Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 3/20 | 0.59 |
| ▸ | PTPRB | P23467 | 13/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19258120 | 1.00 | CCR3 (0.59) | CCR3PTPRBPPARGPPARAGAA | |
| SCHEMBL19258117 | 1.00 | CCR3 (0.59) | CCR3PTPRBPPARGPPARAGAA | |
| SCHEMBL19257971 | 0.86 | PTPRB (0.49) | CCR3PTPRBHTTLMNAMAPT | |
| SCHEMBL10411484 | 0.86 | PTPRB (0.55) | PTPRBHTTLMNAMAPT | |
| SCHEMBL17297218 | 0.86 | PTPRB (0.55) | PTPRBHTTLMNAMAPT | |
| SCHEMBL792620 | 0.81 | PTPN1 (0.56) | PTPRBHTTLMNAMAPT | |
| SCHEMBL14572899 | 0.81 | PTPN1 (0.56) | PTPRBHTTLMNAMAPT | |
| SCHEMBL679411 | 0.80 | PTPRB (0.71) | CCR3PTPRB | |
| SCHEMBL679410 | 0.80 | PTPRB (0.71) | CCR3PTPRB | |
| SCHEMBL23335327 | 0.77 | PTPRB (0.50) | CCR3PTPRBPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017134547-A1 | TUBULYSIN ANALOGS AND METHODS FOR THEIR PREPARATION | PFIZER INC. (US) | 2017-08-10 | — | — | WO | disclosed |