Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.33 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 2/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
| ▸ | RARA | P10276 | 1/20 | 0.30 |
| ▸ | RARB | P10826 | 1/20 | 0.30 |
| ▸ | RARG | P13631 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20228304 | 0.89 | FFAR1 (0.36) | CYP11B1CYP11B2FFAR1GRM5AKR1C3 | |
| SCHEMBL20006703 | 0.88 | PDE3B (0.33) | CYP11B1CYP11B2PDE3BPDE3ARPS6KA3 | |
| SCHEMBL20006719 | 0.88 | PDE3B (0.33) | CYP11B1CYP11B2PDE3BPDE3ARPS6KA3 | |
| SCHEMBL18622099 | 0.85 | PDE3B (0.33) | CYP11B1CYP11B2PDE3BPDE3AFFAR1 | |
| SCHEMBL20005231 | 0.84 | FFAR1 (0.34) | PDE3BPDE3ARPS6KA3FFAR1 | |
| SCHEMBL20005240 | 0.83 | FFAR1 (0.33) | PDE3BPDE3ARPS6KA3FFAR1AKR1C3 | |
| SCHEMBL20005213 | 0.83 | FFAR1 (0.33) | PDE3BPDE3ARPS6KA3FFAR1AKR1C3 | |
| SCHEMBL19999533 | 0.80 | FFAR1 (0.33) | CYP11B1CYP11B2PDE3BPDE3AAR | |
| SCHEMBL19412664 | 0.79 | — | — | |
| SCHEMBL20005223 | 0.79 | GRM5 (0.34) | PDE3BPDE3ARPS6KA3GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3312257-B1 | LIQUID-CRYSTALLINE MEDIUM AND HIGH-FREQUENCY COMPONENTS COMPRISING SAME | MERCK PATENT GMBH (DE) | 2019-11-20 | — | — | EP | disclosed |
| EP-3414300-B1 | LIQUID-CRYSTALLINE MEDIUM AND HIGH-FREQUENCY COMPONENTS COMPRISING SAME | MERCK PATENT GMBH (DE) | 2019-10-30 | — | — | EP | disclosed |
| EP-2982730-B1 | LIQUID-CRYSTALLINE MEDIUM AND HIGH-FREQUENCY COMPONENTS COMPRISING SAME | MERCK PATENT GMBH (DE) | 2019-10-16 | — | — | EP | disclosed |
| EP-3312257-A1 | LIQUID-CRYSTALLINE MEDIUM AND HIGH-FREQUENCY COMPONENTS COMPRISING SAME | Merck Patent GmbH (DE) | 2018-04-25 | — | — | EP | disclosed |
| WO-2017137145-A1 | LIQUID-CRYSTALLINE MEDIUM AND HIGH-FREQUENCY COMPONENTS COMPRISING SAME | MERCK PATENT GMBH (DE) | 2017-08-17 | — | — | WO | disclosed |