Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 12/20 | 0.79 |
| ▸ | RPS6KA2 | Q15349 | 13/20 | 0.78 |
| ▸ | RPS6KA1 | Q15418 | 3/20 | 0.78 |
| ▸ | RPS6KA6 | Q9UK32 | 3/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19252957 | 1.00 | RPS6KA3 (0.79) | RPS6KA3RPS6KA2RPS6KA1RPS6KA6 | |
| SCHEMBL19260227 | 0.91 | RPS6KA3 (0.76) | RPS6KA3RPS6KA2RPS6KA1RPS6KA6 | |
| SCHEMBL19252876 | 0.91 | RPS6KA3 (0.76) | RPS6KA3RPS6KA2RPS6KA1RPS6KA6 | |
| SCHEMBL1988119 | 0.89 | RPS6KA3 (1.00) | RPS6KA3RPS6KA2RPS6KA1RPS6KA6 | |
| SCHEMBL1993377 | 0.89 | RPS6KA3 (1.00) | RPS6KA3RPS6KA2RPS6KA1RPS6KA6 | |
| SCHEMBL19252934 | 0.88 | RPS6KA3 (1.00) | RPS6KA3RPS6KA2RPS6KA1RPS6KA6 | |
| SCHEMBL19260242 | 0.85 | RPS6KA3 (0.57) | RPS6KA3RPS6KA2RPS6KA1RPS6KA6 | |
| SCHEMBL19252889 | 0.82 | RPS6KA3 (0.87) | RPS6KA3RPS6KA2RPS6KA1RPS6KA6 | |
| SCHEMBL19252941 | 0.82 | RPS6KA3 (0.84) | RPS6KA3RPS6KA2RPS6KA1RPS6KA6 | |
| SCHEMBL19252852 | 0.82 | RPS6KA3 (0.86) | RPS6KA3RPS6KA2RPS6KA1RPS6KA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3416964-A1 | CARBOXAMIDE DERIVATIVES USEFUL AS RSK INHIBITORS | Phoenix Molecular Designs (CA) | 2018-12-26 | — | — | EP | disclosed |
| WO-2017141116-A1 | CARBOXAMIDE DERIVATIVES USEFUL AS RSK INHIBITORS | PHOENIX MOLECULAR DESIGNS (CA) | 2017-08-24 | — | — | WO | disclosed |