Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19263274 | 0.90 | MAPT (0.45) | POLBMAPTL3MBTL1NOTUMSMN1; SMN2 | |
| SCHEMBL19263008 | 0.90 | MAPT (0.45) | POLBMAPTL3MBTL1SMN1; SMN2MEN1 | |
| SCHEMBL19263270 | 0.89 | NPC1 (0.46) | POLBMAPTL3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL19263012 | 0.89 | MAPT (0.44) | POLBMAPTL3MBTL1NOTUMSMN1; SMN2 | |
| SCHEMBL19263307 | 0.89 | MAPT (0.56) | POLBMAPTL3MBTL1NOTUMSMN1; SMN2 | |
| SCHEMBL19263005 | 0.87 | MAPT (0.43) | POLBMAPTL3MBTL1NOTUMSMN1; SMN2 | |
| SCHEMBL19263251 | 0.86 | PPARD (0.45) | POLBMAPTL3MBTL1SMN1; SMN2MEN1 | |
| SCHEMBL19263277 | 0.86 | MRGPRX4 (0.42) | POLBMAPTL3MBTL1SMN1; SMN2MEN1 | |
| SCHEMBL19263240 | 0.85 | MAPT (0.41) | POLBMAPTL3MBTL1SMN1; SMN2MEN1 | |
| SCHEMBL19263276 | 0.83 | MAPT (0.45) | POLBMAPTL3MBTL1NOTUMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9738673-B1 | Ferrocene derivative, preparation method and use thereof | XIAMEN INSTITUTE OF RARE EARTH MATERIALS (CN) | 2017-08-22 | — | — | US | disclosed |