Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 5/20 | 0.37 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.30 |
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4235758 | 0.89 | CSF1R (0.37) | CSF1R | |
| SCHEMBL3715632 | 0.83 | CSF1R (0.38) | CSF1R | |
| SCHEMBL19264714 | 0.81 | CSF1R (0.35) | CSF1R | |
| SCHEMBL19264758 | 0.77 | CSF1R (0.35) | CSF1R | |
| SCHEMBL19264353 | 0.73 | CSF1R (0.31) | CSF1R | |
| SCHEMBL13884096 | 0.72 | CSF1R (0.53) | CSF1R | |
| SCHEMBL25210432 | 0.72 | CSF1R (0.38) | CSF1R | |
| SCHEMBL19264394 | 0.71 | CSF1R (0.32) | CSF1R | |
| SCHEMBL19264296 | 0.71 | CSF1R (0.32) | CSF1R | |
| SCHEMBL19264733 | 0.71 | MALT1 (0.36) | CSF1RCYP2C8MOGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3208269-A1 | INHIBITORS OF C-FMS KINASE | Janssen Pharmaceutica N.V. (BE) | 2017-08-23 | — | — | EP | disclosed |