SCHEMBL19264725

SCHEMBL19264725

CC1(C)CC=C(c2cc(C3C[C@H]4C=C[C@@H](C3)O4)ccc2NC(=O)c2nc(C#N)c[nH]2)CC1

nearest known ligand 0.56

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ CSF1R P07333 8/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23808597 1.00 CSF1R (0.56) CSF1R
SCHEMBL19264807 0.90 CSF1R (0.50) CSF1R
SCHEMBL23808413 0.89 CSF1R (0.51) CSF1R
SCHEMBL23808704 0.87 CSF1R (0.54) CSF1R
SCHEMBL23808412 0.87 CSF1R (0.54) CSF1R
SCHEMBL19264617 0.87 CSF1R (0.54) CSF1R
SCHEMBL1864639 0.87 CSF1R (0.74) CSF1R
SCHEMBL3165017 0.87 CSF1R (0.58) CSF1R
SCHEMBL23808650 0.86 CSF1R (0.56) CSF1R
SCHEMBL23808466 0.86 CSF1R (0.56) CSF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3208269-B1 INHIBITORS OF C-FMS KINASE JANSSEN PHARMACEUTICA NV (BE) 2021-09-15 — — EP disclosed
EP-3208269-A1 INHIBITORS OF C-FMS KINASE Janssen Pharmaceutica N.V. (BE) 2017-08-23 — — EP disclosed
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