Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 18/20 | 0.60 |
| ▸ | AVPR1A | P37288 | 18/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1441282 | 0.89 | AVPR2 (0.62) | AVPR2AVPR1A | |
| SCHEMBL19265199 | 0.89 | AVPR2 (0.61) | AVPR2AVPR1A | |
| SCHEMBL13158418 | 0.86 | AVPR2 (0.65) | AVPR2AVPR1A | |
| SCHEMBL19265324 | 0.84 | AVPR2 (0.66) | AVPR2AVPR1AMAPT | |
| SCHEMBL19265163 | 0.84 | AVPR2 (0.57) | AVPR2AVPR1A | |
| SCHEMBL19265187 | 0.83 | AVPR2 (0.59) | AVPR2AVPR1A | |
| SCHEMBL19265288 | 0.82 | AVPR2 (0.59) | AVPR2AVPR1A | |
| SCHEMBL19265147 | 0.82 | AVPR2 (0.67) | AVPR2AVPR1A | |
| SCHEMBL19265171 | 0.82 | AVPR2 (0.65) | AVPR2AVPR1AMAPT | |
| SCHEMBL19265165 | 0.82 | AVPR2 (0.67) | AVPR2AVPR1AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408751-B1 | Substituted 2-acetamido-5-aryl-1,2,4-triazolones and use thereof | BAYER IP GMBH (DE) | 2017-08-23 | — | — | EP | disclosed |