Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 18/20 | 0.59 |
| ▸ | AVPR1A | P37288 | 18/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3446893 | 0.93 | AVPR2 (0.66) | AVPR2AVPR1ATP53MAPT | |
| SCHEMBL19265303 | 0.91 | AVPR2 (0.54) | AVPR2AVPR1ATP53MAPT | |
| SCHEMBL19265289 | 0.90 | AVPR2 (0.58) | AVPR2AVPR1ATP53MAPT | |
| SCHEMBL3447956 | 0.89 | AVPR2 (0.74) | AVPR2AVPR1A | |
| SCHEMBL19265090 | 0.89 | AVPR2 (0.59) | AVPR2AVPR1ATP53MAPT | |
| SCHEMBL19265107 | 0.88 | AVPR2 (0.57) | AVPR2AVPR1ATP53MAPT | |
| SCHEMBL19265140 | 0.88 | AVPR2 (0.60) | AVPR2AVPR1ATP53MAPT | |
| SCHEMBL19265159 | 0.87 | AVPR2 (0.62) | AVPR2AVPR1ATP53MAPT | |
| SCHEMBL19265297 | 0.87 | AVPR2 (0.62) | AVPR2AVPR1A | |
| SCHEMBL19265166 | 0.86 | AVPR2 (0.65) | AVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408751-B1 | Substituted 2-acetamido-5-aryl-1,2,4-triazolones and use thereof | BAYER IP GMBH (DE) | 2017-08-23 | — | — | EP | disclosed |