Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 2/20 | 0.45 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 4/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19265168 | 0.91 | ATM (0.40) | AVPR2AVPR1AATMCTSLMAPT | |
| SCHEMBL19265086 | 0.89 | AVPR2 (0.44) | AVPR2AVPR1ADRD2ATMPOLB | |
| SCHEMBL10217134 | 0.83 | AVPR2 (0.51) | AVPR2AVPR1ADRD2ATMPOLB | |
| SCHEMBL10217329 | 0.82 | AVPR2 (0.45) | AVPR2AVPR1ADRD2ATMPOLB | |
| SCHEMBL10217138 | 0.82 | AVPR2 (0.50) | AVPR2AVPR1ADRD2ATMPOLB | |
| SCHEMBL257267 | 0.81 | AVPR2 (0.45) | AVPR2AVPR1ADRD2ATMPOLB | |
| SCHEMBL10216786 | 0.81 | AVPR2 (0.46) | AVPR2AVPR1ADRD2ATMPOLB | |
| SCHEMBL19265304 | 0.81 | AVPR2 (0.46) | AVPR2AVPR1AATMPOLBMAPT | |
| SCHEMBL381756 | 0.80 | CTSA (0.51) | AVPR2AVPR1A | |
| SCHEMBL10216968 | 0.80 | AVPR2 (0.46) | AVPR2AVPR1ADRD2ATMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408751-B1 | Substituted 2-acetamido-5-aryl-1,2,4-triazolones and use thereof | BAYER IP GMBH (DE) | 2017-08-23 | — | — | EP | disclosed |