Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 20/20 | 0.90 |
| ▸ | CDC37 | Q16543 | 2/20 | 0.71 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4997743 | 0.94 | HSP90AA1 (1.00) | HSP90AA1CDC37HSP90B1 | |
| SCHEMBL1743406 | 0.89 | HSP90AA1 (0.90) | HSP90AA1CDC37 | |
| SCHEMBL2993375 | 0.89 | HSP90AA1 (0.89) | HSP90AA1CDC37HSP90B1 | |
| SCHEMBL12454183 | 0.87 | HSP90AA1 (0.90) | HSP90AA1CDC37HSP90B1 | |
| SCHEMBL18431833 | 0.87 | HSP90AA1 (0.90) | HSP90AA1CDC37HSP90B1 | |
| SCHEMBL18431832 | 0.87 | HSP90AA1 (0.90) | HSP90AA1CDC37HSP90B1 | |
| SCHEMBL1742677 | 0.85 | HSP90AA1 (1.00) | HSP90AA1CDC37HSP90B1 | |
| SCHEMBL1743323 | 0.85 | HSP90AA1 (1.00) | HSP90AA1CDC37HSP90B1 | |
| SCHEMBL4136026 | 0.84 | HSP90AA1 (1.00) | HSP90AA1CDC37HSP90B1 | |
| SCHEMBL24725170 | 0.84 | HSP90AA1 (0.82) | HSP90AA1CDC37HSP90B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3709022-A1 | USES OF LABELED HSP90 INHIBITORS | Sloan-Kettering Institute for Cancer Research (US) | 2020-09-16 | — | — | EP | disclosed |
| EP-3208615-A2 | USES OF LABELED HSP90 INHIBITORS | Sloan Kettering Institute For Cancer Research (US) | 2017-08-23 | — | — | EP | disclosed |