Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 18/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | KDM6B | O15054 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19268156 | 0.95 | EGFR (0.38) | EGFRKDRPDGFRBKDM4CKDM6B | |
| SCHEMBL17615608 | 0.81 | KDM4C (0.44) | EGFRKDRPDGFRBKDM4C | |
| SCHEMBL22163336 | 0.77 | KDM4C (0.50) | KDM4CKDM6B | |
| SCHEMBL17615607 | 0.76 | KDM4C (0.42) | KDM4C | |
| SCHEMBL22163584 | 0.76 | KDM4C (0.59) | KDM4C | |
| SCHEMBL19268160 | 0.75 | KDM4C (0.42) | KDM4C | |
| SCHEMBL19268159 | 0.75 | KDM4C (0.43) | KDM4C | |
| SCHEMBL19268161 | 0.74 | LATS1 (0.42) | KDM4C | |
| SCHEMBL17615612 | 0.74 | KDM4C (0.47) | EGFRKDRKDM4CPDGFRA | |
| SCHEMBL19268157 | 0.74 | KDM4C (0.42) | KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170240546-A1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RESEARCH, INC. (US) | 2017-08-24 | — | — | US | disclosed |
| US-20170240546-A1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RESEARCH, INC. (US) | 2017-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170240546-A1 | HISTONE DEMETHYLASE INHIBITORS | KDM1B, KDM1A, KDM5C | EGFR 2920/4885KDR 4487/4885PDGFRB 1806/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.