Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | RAC2 | P15153 | 1/20 | 0.32 |
| ▸ | RAC3 | P60763 | 1/20 | 0.32 |
| ▸ | CDC42 | P60953 | 1/20 | 0.32 |
| ▸ | RAC1 | P63000 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.32 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.32 |
| ▸ | TSPO | P30536 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19270861 | 0.96 | KDM4E (0.34) | KDM4EATML3MBTL1PTGER4RAC2 | |
| SCHEMBL19269378 | 0.93 | KDM4E (0.32) | KDM4EATML3MBTL1RAC2RAC3 | |
| SCHEMBL19269527 | 0.93 | KDM4E (0.32) | KDM4EATML3MBTL1RAC2RAC3 | |
| SCHEMBL19269220 | 0.91 | ATM (0.33) | KDM4EATML3MBTL1PTGER4RAC2 | |
| SCHEMBL19269044 | 0.89 | ATM (0.39) | KDM4EATML3MBTL1PTGER4RAC2 | |
| SCHEMBL19269536 | 0.89 | ATM (0.41) | KDM4EATML3MBTL1PTGER4RAC2 | |
| SCHEMBL19269825 | 0.89 | ATM (0.41) | KDM4EATML3MBTL1PTGER4RAC2 | |
| SCHEMBL20413203 | 0.89 | PDE3B (0.34) | KDM4EATML3MBTL1PTGER4RAC2 | |
| SCHEMBL19270868 | 0.89 | KDM4E (0.35) | KDM4EATML3MBTL1PTGER4RAC2 | |
| SCHEMBL19269103 | 0.87 | ATM (0.35) | ATMKDM1AAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170244049-A1 | ORGANIC LIGHT-EMITTING DIODE MATERIALS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170244049-A1 | ORGANIC LIGHT-EMITTING DIODE MATERIALS | CYBA, DDT, DRD1 | KDM4E 2858/4885ATM 1981/4885L3MBTL1 24/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.