SCHEMBL19273665

SCHEMBL19273665

CC(C)(C)C(=O)Oc1ccc2c(c1)C(c1ccc(OC3CCN(CCCF)C3)cc1)=CCCC2

nearest known ligand 0.55

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 19/20 0.55
AGTR2 P50052 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31739217 1.00 ESR1 (0.55) ESR1AGTR2
SCHEMBL19131981 1.00 ESR1 (0.55) ESR1AGTR2
SCHEMBL19132033 0.94 ESR1 (0.56) ESR1AGTR2
SCHEMBL19273781 0.94 ESR1 (0.56) ESR1AGTR2
SCHEMBL31739242 0.94 ESR1 (0.56) ESR1AGTR2
SCHEMBL20165165 0.89 ESR1 (0.54) ESR1AGTR2
SCHEMBL20165168 0.89 ESR1 (0.54) ESR1AGTR2
SCHEMBL29756882 0.89 ESR1 (0.54) ESR1AGTR2
SCHEMBL24022240 0.87 ESR1 (0.63) ESR1AGTR2
SCHEMBL31739214 0.87 ESR1 (0.63) ESR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3524600-B1 PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF NOVEL SUBSTITUTED 6,7-DIHYDRO-5H-BENZO[7]ANNULENE COMPOUNDS SANOFI SA (FR) 2021-11-17 EP disclosed
WO-2017140669-A1 6,7-DIHYDRO-5H-BENZO[7]ANNULENE DERIVATIVES AS ESTROGEN RECEPTOR MODULATORS SANOFI (FR) 2017-08-24 WO disclosed