SCHEMBL19276384

SCHEMBL19276384

CC1COCCN1c1cc(OC(C)(C)C)nc(N2CCCC[C@@H]2c2ccccc2)c1

nearest known ligand 0.58

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PIK3C3 Q8NEB9 20/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19259460 1.00 PIK3C3 (0.58) PIK3C3
SCHEMBL19276371 0.97 PIK3C3 (0.57) PIK3C3
SCHEMBL19259466 0.97 PIK3C3 (0.57) PIK3C3
SCHEMBL19259519 0.91 PIK3C3 (0.54) PIK3C3
SCHEMBL19275767 0.91 PIK3C3 (0.54) PIK3C3
SCHEMBL19259426 0.90 PIK3C3 (0.59) PIK3C3
SCHEMBL22170287 0.90 PIK3C3 (0.59) PIK3C3
SCHEMBL19259515 0.88 PIK3C3 (0.60) PIK3C3
SCHEMBL19276468 0.88 PIK3C3 (0.60) PIK3C3
SCHEMBL19276377 0.87 PIK3C3 (0.62) PIK3C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3416957-B1 6-HETEROCYCLYL-4-MORPHOLIN-4-YLPYRIDIN-2-ONE COMPOUNDS USEFUL FOR THE TREATMENT OF CANCER AND DIABETES SPRINT BIOSCIENCE AB (SE) 2020-07-01 EP disclosed
WO-2017140843-A1 6-HETEROCYCLYL-4-MORPHOLIN-4-YLPYRIDINE-2-ONE COMPOUNDS USEFUL FOR THE TREATMENT OF CANCER AND DIABETES SPRINT BIOSCIENCE AB (SE) 2017-08-24 WO disclosed