Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19279323 | 0.93 | BTK (1.00) | BTK | |
| SCHEMBL19279540 | 0.91 | BTK (0.84) | BTK | |
| SCHEMBL19279538 | 0.90 | BTK (1.00) | BTK | |
| SCHEMBL19279714 | 0.90 | BTK (0.81) | BTK | |
| SCHEMBL19279550 | 0.89 | BTK (1.00) | BTK | |
| SCHEMBL19279632 | 0.88 | BTK (1.00) | BTK | |
| SCHEMBL19279572 | 0.88 | BTK (1.00) | BTK | |
| SCHEMBL19279587 | 0.88 | BTK (1.00) | BTK | |
| SCHEMBL25257921 | 0.86 | BTK (0.87) | BTK | |
| SCHEMBL17699670 | 0.86 | BTK (1.00) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3209652-B1 | TRICYCLIC ATROPISOMER COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2020-04-15 | — | — | EP | claimed |
| US-10023534-B2 | Carbazole and tetrahydrocarbazole compounds useful as inhibitors of BTK | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-07-17 | — | — | US | claimed |
| US-20170355673-A1 | TRICYCLIC ATROPISOMER COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2017-12-14 | — | — | US | claimed |
| EP-3209652-A1 | TRICYCLIC ATROPISOMER COMPOUNDS | Bristol-Myers Squibb Company (US) | 2017-08-30 | — | — | EP | claimed |
| CN-107108555-B | Tricyclic atropisomer compounds | 百时美施贵宝公司 | 2020-12-01 | — | — | CN | disclosed |
| EP-3209652-B1 | TRICYCLIC ATROPISOMER COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2020-04-15 | — | — | EP | disclosed |
| EP-3209652-B1 | TRICYCLIC ATROPISOMER COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2020-04-15 | — | — | EP | disclosed |
| US-10023534-B2 | Carbazole and tetrahydrocarbazole compounds useful as inhibitors of BTK | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-07-17 | — | — | US | disclosed |
| US-10023534-B2 | Carbazole and tetrahydrocarbazole compounds useful as inhibitors of BTK | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-07-17 | — | — | US | disclosed |
| US-20170355673-A1 | TRICYCLIC ATROPISOMER COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2017-12-14 | — | — | US | disclosed |
| US-20170355673-A1 | TRICYCLIC ATROPISOMER COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2017-12-14 | — | — | US | disclosed |
| EP-3209652-A1 | TRICYCLIC ATROPISOMER COMPOUNDS | Bristol-Myers Squibb Company (US) | 2017-08-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170355673-A1 | TRICYCLIC ATROPISOMER COMPOUNDS | BTK, LCK, SYK | BTK 1/4885 |
| US-10023534-B2 | Carbazole and tetrahydrocarbazole compounds useful as inhibitors of BTK | BTK, JAK2, SYK | BTK 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.