Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15915971 | 0.87 | ALOX5AP (1.00) | ALOX5APFEN1 | |
| SCHEMBL15915788 | 0.84 | FEN1 (1.00) | ALOX5APFEN1 | |
| SCHEMBL15915022 | 0.83 | FEN1 (1.00) | ALOX5APFEN1 | |
| SCHEMBL20627120 | 0.83 | FEN1 (1.00) | ALOX5APFEN1 | |
| SCHEMBL15915286 | 0.83 | FEN1 (1.00) | ALOX5APFEN1 | |
| SCHEMBL15916162 | 0.83 | FEN1 (1.00) | ALOX5APFEN1 | |
| SCHEMBL15916213 | 0.82 | FEN1 (1.00) | ALOX5APFEN1 | |
| SCHEMBL15936694 | 0.79 | ALOX5AP (0.75) | ALOX5APFEN1 | |
| SCHEMBL15916227 | 0.78 | FEN1 (1.00) | ALOX5APFEN1 | |
| SCHEMBL20627448 | 0.77 | ALOX5AP (0.73) | ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9884878-B2 | FLAP modulators | JANSSEN PHARMACEUTICA NV (BE) | 2018-02-06 | — | — | US | disclosed |
| US-9745328-B2 | Flap modulators | JANSSEN PHARMACEUTICA NV (BE) | 2017-08-29 | — | — | US | disclosed |