Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | QPCT | Q16769 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17470179 | 0.75 | HTT (0.44) | HTTTDP1MEN1KMT2AALPL | |
| SCHEMBL26127385 | 0.70 | HTT (0.57) | HTTTDP1MEN1KMT2AALPL | |
| SCHEMBL17466735 | 0.70 | HTT (0.47) | HTTTDP1MEN1KMT2AALPL | |
| SCHEMBL13949688 | 0.69 | HTT (0.55) | HTTTDP1MEN1KMT2AALPL | |
| SCHEMBL10488928 | 0.68 | HTT (0.54) | HTTTDP1MEN1KMT2AALPL | |
| SCHEMBL15398440 | 0.68 | HTT (0.54) | HTTTDP1MEN1KMT2AALPL | |
| SCHEMBL27773043 | 0.67 | HSD17B10 (0.53) | HTTTDP1MEN1KMT2AALPL | |
| SCHEMBL5455317 | 0.66 | HSD17B10 (0.64) | HTTTDP1MEN1KMT2ALMNA | |
| SCHEMBL13810445 | 0.65 | HSD17B10 (0.52) | HTTTDP1MEN1KMT2ALMNA | |
| SCHEMBL10710110 | 0.65 | HSD17B10 (0.52) | TDP1MEN1KMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9744528-B2 | Metallorganocatalysis for asymmetric transformations | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2017-08-29 | — | — | US | disclosed |