Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | QPCT | Q16769 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17470003 | 0.82 | GAA (0.38) | HTTQPCTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL19286292 | 0.80 | HTT (0.42) | HTTATMALPLALPIALPG | |
| SCHEMBL17470001 | 0.79 | MAPT (0.51) | HTTKMT2AMEN1TDP1SMN1; SMN2 | |
| SCHEMBL19286240 | 0.72 | CYP3A4 (0.35) | TDP1GAA | |
| SCHEMBL17469999 | 0.70 | MEN1 (0.34) | KMT2AMEN1TDP1MAPT | |
| SCHEMBL17470000 | 0.69 | SMN1; SMN2 (0.43) | HTTKMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL12951432 | 0.69 | CYP3A4 (0.35) | TDP1GAA | |
| SCHEMBL17470043 | 0.69 | HTT (0.33) | HTTATMALPLALPIALPG | |
| SCHEMBL5455317 | 0.67 | HSD17B10 (0.64) | HTTQPCTKMT2AMEN1TDP1 | |
| SCHEMBL17470179 | 0.67 | HTT (0.44) | HTTATMALPLALPIALPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9744528-B2 | Metallorganocatalysis for asymmetric transformations | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2017-08-29 | — | — | US | disclosed |