SCHEMBL19286607

SCHEMBL19286607

CC(C)(Oc1ccc(C(C)(C)Oc2ccccc2)cc1)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.56
ALDH1A1 P00352 2/20 0.52
ALOX15 P16050 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.42
ESR1 P03372 3/20 0.40
ESR2 Q92731 3/20 0.40
CYP3A4 P08684 1/20 0.40
MAPT P10636 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
CA4 P22748 1/20 0.39
KCNH2 Q12809 3/20 0.38
CCR6 P51684 2/20 0.38
PPARA Q07869 2/20 0.38
LTA4H P09960 2/20 0.38
KIF11 P52732 2/20 0.38
TAAR1 Q96RJ0 1/20 0.37
PPARG P37231 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9331411 0.95 MAPK1 (0.61) MAPK1ALDH1A1ALOX15SMN1; SMN2ESR1
SCHEMBL9332606 0.95 MAPK1 (0.61) MAPK1ALDH1A1ALOX15SMN1; SMN2ESR1
SCHEMBL22951133 0.91 MAPK1 (0.46) MAPK1ALDH1A1ALOX15SMN1; SMN2ESR1
SCHEMBL21191439 0.90 MAPK1 (0.50) MAPK1ALDH1A1ALOX15SMN1; SMN2ESR1
SCHEMBL3773997 0.90 CA4 (0.56) MAPK1ALDH1A1ALOX15MAPTTDP1
SCHEMBL20763441 0.88 ESR1 (0.53) MAPK1ALDH1A1ALOX15ESR1ESR2
SCHEMBL2181406 0.88 MAPK1 (0.43) MAPK1ALDH1A1ALOX15SMN1; SMN2ESR1
SCHEMBL9707201 0.87 MAPK1 (0.52) MAPK1ALDH1A1ALOX15SMN1; SMN2ESR1
SCHEMBL23474364 0.86 MAPK1 (0.42) MAPK1ALDH1A1ALOX15SMN1; SMN2MAPT
SCHEMBL21191327 0.85 ESR1 (0.55) MAPK1ALDH1A1ALOX15ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220119594-A1 POLYARYLENE ETHER KETONE RESIN, PRODUCTION METHOD THEREOF, AND MOLDED PRODUCT DIC CORPORATION (JP) 2022-04-21 US disclosed
US-20210171710-A1 POLYARYLENE ETHER KETONE RESIN AND PRODUCTION METHOD THEREFOR, AND MOLDED ARTICLE DIC CORPORATION (JP) 2021-06-10 US disclosed
WO-2019142942-A1 POLYARYLENE ETHER KETONE RESIN AND PRODUCTION METHOD THEREOF, AND MOLDED BODY DIC株式会社 2019-07-25 WO disclosed
US-10035896-B2 Salts of pyrophosphonic acid as flame retardants LANXESS SOLUTIONS US INC. (US) 2018-07-31 US disclosed
US-9752011-B2 Phosphorus containing flame retardants LANXESS SOLUTIONS US INC. (US) 2017-09-05 US disclosed
US-9745449-B2 Phosphorus containing flame retardants LANXESS SOLUTIONS US INC. (US) 2017-08-29 US disclosed