Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25485199 | 0.81 | AR (0.30) | — | |
| SCHEMBL20968408 | 0.73 | KDM4E (0.35) | KDM4EALDH1A1HTT | |
| SCHEMBL19703658 | 0.73 | — | — | |
| SCHEMBL19704560 | 0.69 | DPP4 (0.32) | — | |
| SCHEMBL25977405 | 0.69 | MAPT (0.34) | — | |
| SCHEMBL22472680 | 0.68 | — | — | |
| SCHEMBL23127791 | 0.68 | — | — | |
| SCHEMBL25446419 | 0.67 | SMN1; SMN2 (0.39) | KDM4EALDH1A1HTT | |
| SCHEMBL25155026 | 0.67 | TSHR (0.34) | — | |
| SCHEMBL21365276 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11725064-B2 | Chimeric small molecules for the recruitment of antibodies to cancer cells | YALE UNIVERSITY (US) | 2023-08-15 | — | — | US | disclosed |
| US-20220023428-A1 | CHIMERIC SMALL MOLECULES FOR THE RECRUITMENT OF ANTIBODIES TO CANCER CELLS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2022-01-27 | — | — | US | disclosed |
| US-10633374-B2 | Small molecule based antibody-recruiting compounds for cancer treatment | YALE UNIVERSITY (US) | 2020-04-28 | — | — | US | disclosed |
| US-9745334-B2 | Cytotoxic-drug delivering molecules targeting HIV (CDM-Hs), cytotoxic activity against the human immunodeficiency virus and methods of use | YALE UNIVERSITY (US) | 2017-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11725064-B2 | Chimeric small molecules for the recruitment of antibodies to cancer cells | BRDT, PAICS, KLK3 | KDM4E 971/4885ALDH1A1 2479/4885HTT 2925/4885 |
| US-20220023428-A1 | CHIMERIC SMALL MOLECULES FOR THE RECRUITMENT OF ANTIBODIES TO CANCER CELLS | BRDT, PAICS, KLK3 | KDM4E 971/4885ALDH1A1 2479/4885HTT 2925/4885 |
| US-10633374-B2 | Small molecule based antibody-recruiting compounds for cancer treatment | PLAUR, C5AR1, C3AR1 | KDM4E 3381/4885ALDH1A1 3982/4885HTT 4470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.