Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 9/20 | 0.82 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.57 |
| ▸ | HIF1AN | Q9NWT6 | 4/20 | 0.56 |
| ▸ | ODC1 | P11926 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16694382 | 0.90 | HIF1A (1.00) | HIF1AHSP90AA1 | |
| SCHEMBL16694335 | 0.90 | HIF1A (1.00) | HIF1AHSP90AA1 | |
| SCHEMBL16694336 | 0.90 | HIF1A (1.00) | HIF1AHSP90AA1 | |
| SCHEMBL16867649 | 0.87 | HIF1A (0.66) | HIF1AHSP90AA1HIF1ANODC1 | |
| SCHEMBL16694376 | 0.87 | HIF1A (0.66) | HIF1AHSP90AA1HIF1ANODC1 | |
| SCHEMBL16694375 | 0.87 | HIF1A (0.66) | HIF1AHSP90AA1HIF1ANODC1 | |
| SCHEMBL19365716 | 0.86 | HIF1A (0.76) | HIF1AHSP90AA1 | |
| SCHEMBL16865493 | 0.82 | HIF1A (0.84) | HIF1AHSP90AA1 | |
| SCHEMBL16865494 | 0.82 | HIF1A (0.84) | HIF1AHSP90AA1 | |
| SCHEMBL16865550 | 0.82 | HIF1A (0.84) | HIF1AHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9745280-B2 | Compound or pharmaceutically acceptable salt thereof, and pharmaceutical composition containing same as active ingredient | SNU R&DB FOUNDATION (KR) | 2017-08-29 | — | — | US | disclosed |