Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.36 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | POLQ | O75417 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19288241 | 0.91 | PFKFB3 (0.54) | PFKFB3NPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL19288238 | 0.84 | PFKFB3 (0.67) | PFKFB3NPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL15058769 | 0.83 | PFKFB3 (0.73) | PFKFB3NPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL19288295 | 0.83 | PFKFB3 (0.43) | PFKFB3TP53KDM4EMAPTTSHR | |
| SCHEMBL19288332 | 0.79 | PFKFB3 (0.42) | PFKFB3TP53SMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL19288400 | 0.78 | PFKFB3 (0.41) | PFKFB3NPC1RAB9ASMN1; SMN2POLQ | |
| SCHEMBL19288227 | 0.77 | PFKFB3 (0.44) | PFKFB3RAB9AL3MBTL1KDM4EMAPT | |
| SCHEMBL19288247 | 0.75 | KDM4E (0.39) | PFKFB3SMN1; SMN2KDM4E | |
| SCHEMBL19288303 | 0.74 | PFKFB3 (0.52) | PFKFB3KDM4EMAPTMEN1KMT2A | |
| SCHEMBL19288480 | 0.73 | PFKFB3 (0.42) | PFKFB3NPC1TP53RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2794009-B1 | BISARYLSULFONAMIDES USEFUL IN THE TREATMENT OF INFLAMMATION AND CANCER | KANCERA AB (SE) | 2017-08-30 | — | — | EP | disclosed |