Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | CPA1 | P15085 | 1/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19291644 | 0.88 | CYSLTR2 (0.45) | CYSLTR2CYSLTR1TAAR1MAOBBCHE | |
| SCHEMBL13881670 | 0.85 | TAAR1 (0.43) | CYSLTR2CYSLTR1TAAR1MAOB | |
| SCHEMBL18550938 | 0.85 | TAAR1 (0.43) | CYSLTR2CYSLTR1TAAR1MAOB | |
| SCHEMBL18550942 | 0.85 | TAAR1 (0.43) | CYSLTR2CYSLTR1TAAR1 | |
| SCHEMBL18293493 | 0.85 | TAAR1 (0.43) | CYSLTR2CYSLTR1TAAR1MAOB | |
| SCHEMBL2204997 | 0.84 | CYSLTR2 (0.43) | CYSLTR2CYSLTR1TAAR1TSHRMAPK1 | |
| SCHEMBL29818812 | 0.84 | CYSLTR2 (0.43) | CYSLTR2CYSLTR1TAAR1TSHRMAPK1 | |
| SCHEMBL2204823 | 0.84 | CYSLTR2 (0.43) | CYSLTR2CYSLTR1TAAR1TSHRMAPK1 | |
| SCHEMBL29819310 | 0.84 | CYSLTR2 (0.43) | CYSLTR2CYSLTR1TAAR1TSHRMAPK1 | |
| SCHEMBL2204829 | 0.84 | CYSLTR2 (0.43) | CYSLTR2CYSLTR1TAAR1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3210966-A1 | ALKOXYPHENYLPROPYLAMINES FOR THE TREATMENT OF AGE-RELATED MACULAR DEGENERATION | Acucela, Inc. (US) | 2017-08-30 | — | — | EP | disclosed |