Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN2A | Q99250 | 2/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.37 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | COMT | P21964 | 1/20 | 0.36 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19292150 | 0.85 | PDE10A (0.46) | NPY5RPDE10A | |
| SCHEMBL19292508 | 0.83 | PDE10A (0.55) | PDE10A | |
| SCHEMBL19291976 | 0.81 | PDE10A (0.43) | PDE10ASCN10AS1PR1S1PR4S1PR3 | |
| SCHEMBL19292422 | 0.80 | PDE10A (0.42) | PDE10AS1PR1S1PR4S1PR3S1PR5 | |
| SCHEMBL19292461 | 0.80 | SCN10A (0.49) | NPY5RPDE10ASCN10ACCNB2CDK1 | |
| SCHEMBL19292239 | 0.80 | HDAC1 (0.42) | PDE10ASCN10AS1PR1S1PR4S1PR3 | |
| SCHEMBL19292339 | 0.80 | PDE10A (0.41) | PDE10A | |
| SCHEMBL19292031 | 0.79 | S1PR1 (0.35) | PDE10ASCN10AS1PR1S1PR4S1PR3 | |
| SCHEMBL19292412 | 0.78 | PDE10A (0.37) | PDE10AS1PR1S1PR4S1PR5 | |
| SCHEMBL19291980 | 0.78 | PDE10A (0.37) | PDE10ASCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2914589-B1 | COMPOUNDS FOR USE IN THE TREATMENT OF PARASITIC DISEASES | IRBM - SCIENCE PARK S P A (IT) | 2017-08-30 | — | — | EP | disclosed |