Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLN | Q9BYT8 | 2/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 7/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | PYGL | P06737 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.39 |
| ▸ | PADI3 | Q9ULW8 | 1/20 | 0.39 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.39 |
| ▸ | PADI2 | Q9Y2J8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19292325 | 0.88 | PDE10A (0.42) | NLNPDE10AHDAC1PYGLPADI1 | |
| SCHEMBL19292044 | 0.88 | PDE10A (0.39) | NLNPDE10AHDAC1 | |
| SCHEMBL19291965 | 0.88 | HDAC1 (0.40) | NLNPDE10AHDAC1 | |
| SCHEMBL19292035 | 0.86 | NPC1 (0.43) | PDE10AHDAC1 | |
| SCHEMBL19291971 | 0.86 | NPC1 (0.44) | HDAC1CYP11B1CYP11B2 | |
| SCHEMBL19292354 | 0.86 | PDE10A (0.42) | PDE10AHDAC1PADI1PADI3PADI4 | |
| SCHEMBL19292218 | 0.86 | PDE10A (0.43) | PDE10AHDAC1 | |
| SCHEMBL19292508 | 0.85 | PDE10A (0.55) | PDE10APADI1PADI3PADI4PADI2 | |
| SCHEMBL22505295 | 0.84 | NLN (0.46) | NLNPDE10AHDAC1PYGLCYP11B1 | |
| SCHEMBL19292389 | 0.84 | NLN (0.44) | NLNPDE10AHDAC1PYGLCYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2914589-B1 | COMPOUNDS FOR USE IN THE TREATMENT OF PARASITIC DISEASES | IRBM - SCIENCE PARK S P A (IT) | 2017-08-30 | — | — | EP | disclosed |