SCHEMBL19295993

SCHEMBL19295993

CC(c1ccn2ccnc2c1)N1CCN(c2ncc(C(F)(F)F)cn2)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
OGA O60502 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25900282 0.86 OGA (0.76) OGA
SCHEMBL17551228 0.80 OGA (1.00) OGA
SCHEMBL19461163 0.80 OGA (1.00) OGA
SCHEMBL19473612 0.80 OGA (1.00) OGA
SCHEMBL17551230 0.80 OGA (1.00) OGA
SCHEMBL25898586 0.77 OGA (0.62) OGA
SCHEMBL19295787 0.75 OGA (0.72) OGA
SCHEMBL20759335 0.75 OGA (1.00) OGA
SCHEMBL19283894 0.75 OGA (1.00) OGA
SCHEMBL23565458 0.74 OGA (0.70) OGA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3419972-B1 GLYCOSIDASE INHIBITORS ASCENEURON SA (CH) 2023-07-26 EP disclosed
US-11612599-B2 Glycosidase inhibitors ASCENEURON SA (CH) 2023-03-28 US disclosed
EP-3419971-B1 GLYCOSIDASE INHIBITORS ASCENEURON SA (CH) 2022-04-20 EP disclosed
EP-3419971-B1 GLYCOSIDASE INHIBITORS ASCENEURON SA (CH) 2022-04-20 EP disclosed
US-20210186958-A1 GLYCOSIDASE INHIBITORS ASCENEURON SA (CH) 2021-06-24 US disclosed
US-20210186958-A1 GLYCOSIDASE INHIBITORS ASCENEURON SA (CH) 2021-06-24 US disclosed
US-10556902-B2 Glycosidase inhibitors ASCENEURON SA (CH) 2020-02-11 US disclosed
US-10556902-B2 Glycosidase inhibitors ASCENEURON SA (CH) 2020-02-11 US disclosed
US-20190055239-A1 GLYCOSIDASE INHIBITORS ASCENEURON SA (CH) 2019-02-21 US disclosed
US-20190055239-A1 GLYCOSIDASE INHIBITORS ASCENEURON SA (CH) 2019-02-21 US disclosed
WO-2017144639-A1 GLYCOSIDASE INHIBITORS ASCENEURON S. A. (CH) 2017-08-31 WO disclosed
WO-2017144633-A1 GLYCOSIDASE INHIBITORS ASCENEURON S. A. (CH) 2017-08-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11612599-B2 Glycosidase inhibitors ENGASE, GAA, GLA OGA 73/4885
US-10556902-B2 Glycosidase inhibitors ENGASE, GAA, GLA OGA 69/4885
US-20210186958-A1 GLYCOSIDASE INHIBITORS ENGASE, GAA, GLA OGA 73/4885
US-20190055239-A1 GLYCOSIDASE INHIBITORS ENGASE, GAA, GLA OGA 69/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.