Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 2/20 | 0.54 |
| ▸ | CLK2 | P49760 | 5/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.44 |
| ▸ | MAPK7 | Q13164 | 2/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | CLK3 | P49761 | 1/20 | 0.41 |
| ▸ | MELK | Q14680 | 4/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.38 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4285440 | 0.85 | OGA (0.53) | OGACLK2LRRK2GSK3BDYRK1A | |
| SCHEMBL19283852 | 0.85 | OGA (0.53) | OGACLK2LRRK2MAPK7GSK3B | |
| SCHEMBL23945623 | 0.82 | OGA (0.50) | OGACLK2LRRK2MAPK7GSK3B | |
| SCHEMBL19296123 | 0.82 | DDB1 (0.52) | OGACLK2LRRK2MAPK7GSK3B | |
| Hydrochloric Acid SCHEMBL19283848 | 0.81 | DDB1 (0.51) | OGACLK2LRRK2MAPK7GSK3B | |
| SCHEMBL19283870 | 0.79 | DDB1 (0.63) | OGADDB1CRBNALDH1A1BTK | |
| Hydrochloric Acid SCHEMBL21640209 | 0.77 | OGA (0.46) | OGACLK2LRRK2MAPK7GSK3B | |
| SCHEMBL23945144 | 0.76 | OGA (0.46) | OGACLK2LRRK2MAPK7GSK3B | |
| SCHEMBL23945349 | 0.76 | OGA (0.46) | OGACLK2LRRK2MAPK7GSK3B | |
| SCHEMBL22098019 | 0.75 | OGA (0.44) | OGACLK2LRRK2MAPK7GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017144633-A1 | GLYCOSIDASE INHIBITORS | ASCENEURON S. A. (CH) | 2017-08-31 | — | — | WO | disclosed |
| WO-2017144639-A1 | GLYCOSIDASE INHIBITORS | ASCENEURON S. A. (CH) | 2017-08-31 | — | — | WO | disclosed |