SCHEMBL19296390

SCHEMBL19296390

CCCNC(Cc1ccc2ccccc2c1)C(=O)NCCCCC(NC(=O)NC(CCC(=O)O)C(=O)O)C(=O)O

nearest known ligand 0.70

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 19/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19303442 0.95 FOLH1 (0.72) FOLH1
SCHEMBL19296400 0.91 FOLH1 (0.70) FOLH1
SCHEMBL24123178 0.90 FOLH1 (0.73) FOLH1
SCHEMBL21249161 0.89 FOLH1 (0.74) FOLH1
SCHEMBL29340071 0.89 FOLH1 (0.74) FOLH1
SCHEMBL29338620 0.87 FOLH1 (0.74) FOLH1
SCHEMBL22984225 0.87 FOLH1 (0.69) FOLH1
SCHEMBL29678975 0.86 FOLH1 (0.71) FOLH1
SCHEMBL29678976 0.86 FOLH1 (0.71) FOLH1
SCHEMBL17705986 0.86 FOLH1 (0.76) FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170246327-A1 18F-TAGGED INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA), THEIR USE AS IMAGING AGENTS AND PHARMACEUTICAL AGENTS FOR THE TREATMENT OF PROSTATE CANCER Ruprecht-Karls-Universität Heidelberg (DE) 2017-08-31 — — US disclosed
US-20170246327-A1 18F-TAGGED INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA), THEIR USE AS IMAGING AGENTS AND PHARMACEUTICAL AGENTS FOR THE TREATMENT OF PROSTATE CANCER Ruprecht-Karls-Universität Heidelberg (DE) 2017-08-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170246327-A1 18F-TAGGED INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA), THEIR USE AS IMAGING AGENTS AND PHARMACEUTICAL AGENTS FOR THE TREATMENT OF PROSTATE CANCER KLK3, FOLH1, PSMA6 FOLH1 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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