Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | NCOA2 | Q15596 | 3/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 3/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | DDR1 | Q08345 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.30 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19299798 | 0.93 | POLB (0.40) | POLBALDH1A1HPGDPPARGNCOA2 | |
| SCHEMBL18072957 | 0.89 | POLB (0.41) | POLBALDH1A1HPGDPPARGNCOA2 | |
| SCHEMBL19712029 | 0.89 | POLB (0.41) | POLBALDH1A1HPGDPPARGNCOA2 | |
| SCHEMBL18072962 | 0.87 | POLB (0.41) | POLBALDH1A1HPGDPPARGNCOA2 | |
| SCHEMBL19299827 | 0.86 | POLB (0.40) | POLBALDH1A1HPGDPPARGNCOA2 | |
| SCHEMBL18050266 | 0.85 | POLB (0.40) | POLBALDH1A1HPGDPPARGNCOA2 | |
| SCHEMBL19299828 | 0.85 | POLB (0.40) | POLBALDH1A1HPGDPPARGNCOA2 | |
| SCHEMBL19985657 | 0.84 | POLB (0.39) | POLBALDH1A1HPGDPPARGNCOA2 | |
| SCHEMBL19299800 | 0.84 | POLB (0.40) | POLBALDH1A1HPGDPPARGNCOA2 | |
| SCHEMBL19299825 | 0.84 | POLB (0.40) | POLBALDH1A1HPGDPPARGNCOA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017144341-A1 | CONDENSED BICYCLIC HETEROCYCLE DERIVATIVES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-08-31 | — | — | WO | disclosed |