Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 5/20 | 0.44 |
| ▸ | CA2 | P00918 | 5/20 | 0.44 |
| ▸ | CA12 | O43570 | 4/20 | 0.44 |
| ▸ | CA9 | Q16790 | 4/20 | 0.44 |
| ▸ | CTSK | P43235 | 4/20 | 0.41 |
| ▸ | CTSS | P25774 | 3/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | STK17B | O94768 | 1/20 | 0.40 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.40 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12666362 | 1.00 | MEN1 (0.62) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL7730493 | 1.00 | MEN1 (0.62) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL8062203 | 0.95 | TDP1 (0.59) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL10190369 | 0.95 | TDP1 (0.59) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL23168272 | 0.95 | TDP1 (0.59) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL3185091 | 0.91 | MEN1 (0.63) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL5652312 | 0.91 | MEN1 (0.55) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL29325753 | 0.90 | MEN1 (0.53) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL12954841 | 0.90 | MEN1 (0.53) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL14003800 | 0.89 | MEN1 (0.51) | MEN1KMT2AGAATDP1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017147335-A1 | BACTERIAL EFFLUX PUMP INHIBITORS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2017-08-31 | — | — | WO | disclosed |