Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 11/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | KIT | P10721 | 2/20 | 0.51 |
| ▸ | LCK | P06239 | 1/20 | 0.51 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.51 |
| ▸ | FLT1 | P17948 | 1/20 | 0.51 |
| ▸ | DRD1 | P21728 | 1/20 | 0.51 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19302388 | 0.89 | CSF1R (0.73) | CSF1RCYP3A4CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL1267219 | 0.84 | CSF1R (0.57) | CSF1RCYP3A4CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL1267844 | 0.84 | CSF1R (0.77) | CSF1RCYP3A4CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL1267958 | 0.79 | CYP3A4 (0.83) | CSF1RCYP3A4CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL1267483 | 0.78 | CYP3A4 (0.54) | CSF1RCYP3A4CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL857477 | 0.77 | CYP3A4 (0.69) | CSF1RCYP3A4CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL2181556 | 0.77 | CYP3A4 (0.69) | CSF1RCYP3A4CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL14620861 | 0.77 | CYP3A4 (0.69) | CSF1RCYP3A4CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL21304793 | 0.77 | CSF1R (0.59) | CSF1RCYP3A4CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL19302326 | 0.76 | CSF1R (0.58) | CSF1RCYP3A4CYP2C19CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170247370-A1 | COMPOUNDS MODULATING C-FMS AND/OR C-KIT ACTIVITY AND USES THEREFOR | PLEXXIKON INC. | 2017-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170247370-A1 | COMPOUNDS MODULATING C-FMS AND/OR C-KIT ACTIVITY AND USES THEREFOR | KIT, FLT3, FLT1 | CSF1R 4/4885CYP3A4 3847/4885CYP2C19 3327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.