Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | PI4KA | P42356 | 1/20 | 0.50 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.50 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.50 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.50 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.49 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.49 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.49 |
| ▸ | UBA6 | A0AVT1 | 1/20 | 0.44 |
| ▸ | ATG7 | O95352 | 1/20 | 0.44 |
| ▸ | UBA7 | P41226 | 1/20 | 0.44 |
| ▸ | NAE1 | Q13564 | 1/20 | 0.44 |
| ▸ | UBA3 | Q8TBC4 | 1/20 | 0.44 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.44 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.42 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20699831 | 0.91 | RXFP1 (0.52) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL19302803 | 0.90 | RXFP1 (0.51) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL4896950 | 0.89 | PI4KA (0.54) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL12379190 | 0.89 | PI4KA (0.54) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL24450929 | 0.89 | RXFP1 (0.49) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL29695854 | 0.89 | RXFP1 (0.49) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL18571809 | 0.88 | PI4KA (0.62) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL20699834 | 0.88 | PI4KA (0.62) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL18069462 | 0.88 | PI4KA (0.52) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL12379237 | 0.88 | PI4KA (0.62) | RXFP1PI4KAPI4K2BPI4K2API4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017059411-A9 | INHIBITORS OF MENAQUINONE BIOSYNTHESIS | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2017-08-31 | — | — | WO | disclosed |