Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C2G | O75747 | 10/20 | 0.70 |
| ▸ | PIK3CG | P48736 | 6/20 | 0.61 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.61 |
| ▸ | PI4KB | Q9UBF8 | 11/20 | 0.58 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22218931 | 0.89 | PIK3C2G (0.72) | PIK3C2GPIK3CGPIK3CAPI4KBPIK3CD | |
| SCHEMBL17889559 | 0.83 | PIK3C2G (1.00) | PIK3C2GPIK3CGPIK3CAPI4KBPIK3CD | |
| SCHEMBL22336673 | 0.81 | PIK3CD (0.67) | PIK3C2GPIK3CGPIK3CAPI4KBPIK3CD | |
| SCHEMBL22218939 | 0.79 | PIK3C2G (0.64) | PIK3C2GPIK3CGPIK3CAPI4KBPIK3CD | |
| SCHEMBL17889629 | 0.77 | PIK3C2G (0.86) | PIK3C2GPIK3CGPIK3CAPI4KBPIK3CD | |
| SCHEMBL17889529 | 0.77 | PI4KB (0.88) | PIK3C2GPIK3CGPIK3CAPI4KBPIK3CD | |
| SCHEMBL17889591 | 0.77 | PIK3C2G (1.00) | PIK3C2GPIK3CGPIK3CAPI4KBPIK3CD | |
| SCHEMBL17889590 | 0.76 | PIK3C2G (0.87) | PIK3C2GPIK3CGPIK3CAPI4KBPIK3CD | |
| SCHEMBL17904324 | 0.76 | PIK3C2G (0.83) | PIK3C2GPIK3CGPIK3CAPI4KBPIK3CD | |
| SCHEMBL17906227 | 0.76 | PIK3C2G (1.00) | PIK3C2GPIK3CGPIK3CAPI4KBPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020146657-A1 | PI4-KINASE INHIBITORS WITH ANTI-CANCER ACTIVITY | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2020-07-16 | — | — | WO | disclosed |
| WO-2017147526-A1 | PI-KINASE INHIBITORS WITH ANTI-INFECTIVE ACTIVITY | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2017-08-31 | — | — | WO | disclosed |