Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | RECQL | P46063 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.41 |
| ▸ | USP2 | O75604 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19303801 | 0.89 | KDM4E (0.36) | MAPTKDM4EKMT2ARECQLMEN1 | |
| SCHEMBL5816866 | 0.87 | MAPT (0.50) | MAPTKDM4EKMT2ARECQLMEN1 | |
| SCHEMBL30003545 | 0.87 | MAPT (0.50) | MAPTKDM4EKMT2ARECQLMEN1 | |
| SCHEMBL19303803 | 0.84 | KDM4E (0.38) | MAPTKDM4EKMT2ARECQLMEN1 | |
| SCHEMBL5820321 | 0.83 | KDM4E (0.50) | MAPTKDM4EKMT2ARECQLMEN1 | |
| SCHEMBL19303777 | 0.79 | EGFR (0.38) | MAPTKDM4EKMT2ARECQLMEN1 | |
| SCHEMBL5818746 | 0.79 | MAPT (0.63) | MAPTKDM4EKMT2ARECQLMEN1 | |
| SCHEMBL29791770 | 0.79 | MAPT (0.63) | MAPTKDM4EKMT2ARECQLMEN1 | |
| SCHEMBL10494235 | 0.75 | XIAP (0.44) | MAPTKDM4EKMT2ARECQLMEN1 | |
| SCHEMBL10494226 | 0.74 | KDM4E (0.41) | MAPTKDM4EKMT2ARECQLMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3421449-B1 | PRODUCTION METHOD FOR 1,1'-BINAPHTHYL DERIVATIVES | UNIV KYOTO (JP) | 2021-03-31 | — | — | EP | disclosed |
| EP-3421449-A1 | PRODUCTION METHOD FOR 1,1'-BINAPHTHYL DERIVATIVE, AND 1,1'-BINAPHTHYL DERIVATIVE | Kyoto University (JP) | 2019-01-02 | — | — | EP | disclosed |
| WO-2017145716-A1 | PRODUCTION METHOD FOR 1,1'-BINAPHTHYL DERIVATIVE, AND 1,1'-BINAPHTHYL DERIVATIVE | 国立大学法人京都大学 | 2017-08-31 | — | — | WO | disclosed |