Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | PRTN3 | P24158 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28592153 | 1.00 | PPARG (0.47) | PPARGPPARAELANESLC6A4BTN3A1 | |
| SCHEMBL12621317 | 0.86 | ELANE (0.46) | PPARGPPARAELANEBTN3A1ALDH1A1 | |
| SCHEMBL12621325 | 0.85 | TP53 (0.52) | PPARGPPARAELANEBTN3A1ALDH1A1 | |
| SCHEMBL28918364 | 0.85 | TP53 (0.52) | PPARGPPARAELANEBTN3A1ALDH1A1 | |
| SCHEMBL18961988 | 0.84 | ELANE (0.54) | ELANEBTN3A1ALDH1A1PRTN3TP53 | |
| SCHEMBL12621310 | 0.84 | ELANE (0.54) | ELANEBTN3A1ALDH1A1PRTN3TP53 | |
| SCHEMBL19206472 | 0.83 | PPARG (0.44) | PPARGPPARASLC6A4HRH3 | |
| SCHEMBL13875638 | 0.82 | ELANE (0.47) | ELANEBTN3A1ALDH1A1PRTN3TP53 | |
| SCHEMBL18478022 | 0.82 | ELANE (0.47) | ELANEBTN3A1PRTN3TP53 | |
| SCHEMBL16566324 | 0.81 | ELANE (0.46) | PPARGPPARAELANEBTN3A1PRTN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3214090-A1 | THIONUCLEOSIDE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION | Fujifilm Corporation (JP) | 2017-09-06 | — | — | EP | disclosed |