Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1903971 | 0.97 | TSHR (0.30) | — | |
| Iodide SCHEMBL19307330 | 0.95 | — | — | |
| Hydrochloric Acid SCHEMBL8579490 | 0.95 | — | — | |
| Sulfuric Acid SCHEMBL29244342 | 0.84 | — | — | |
| Bromide SCHEMBL28597019 | 0.80 | TSHR (0.32) | — | |
| SCHEMBL22814165 | 0.80 | — | — | |
| SCHEMBL19307323 | 0.78 | MEN1 (0.30) | — | |
| SCHEMBL14837071 | 0.77 | TSHR (0.33) | — | |
| SCHEMBL27244618 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL11295210 | 0.75 | ABCC3 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3354666-B1 | USE OF AN POLYACRYLAMIDE RESIN AS PAPERMAKING ADDITIVE AND PAPER | HARIMA CHEMICALS INC (JP) | 2021-03-10 | — | — | EP | disclosed |
| EP-3354666-A1 | POLYACRYLAMIDE RESIN, PAPERMAKING ADDITIVE AND PAPER | Harima Chemicals, Inc. (JP) | 2018-08-01 | — | — | EP | disclosed |
| US-9908959-B2 | Polyacrylamide resin, papermaking additive, and paper | HARIMA CHEMICALS, INCORPORATED (JP) | 2018-03-06 | — | — | US | disclosed |
| US-20170253683-A1 | POLYACRYLAMIDE RESIN, PAPERMAKING ADDITIVE, AND PAPER | HARIMA CHEMICALS, INCORPORATED (JP) | 2017-09-07 | — | — | US | disclosed |