Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | HRH2 | P25021 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1813642 | 0.90 | MEN1 (0.73) | MEN1KMT2AHRH3GAAALDH1A1 | |
| SCHEMBL2981986 | 0.88 | MEN1 (0.88) | MEN1KMT2AL3MBTL1HRH3ALDH1A1 | |
| SCHEMBL2980200 | 0.88 | KMT2A (0.67) | MEN1KMT2AL3MBTL1HRH3ALDH1A1 | |
| SCHEMBL28475387 | 0.86 | MEN1 (0.65) | MEN1KMT2AL3MBTL1HRH3GAA | |
| SCHEMBL28477489 | 0.85 | MEN1 (0.64) | MEN1KMT2AL3MBTL1HRH3GAA | |
| SCHEMBL16097702 | 0.84 | MEN1 (0.63) | MEN1KMT2AL3MBTL1HRH3MAPT | |
| SCHEMBL8509832 | 0.84 | MEN1 (0.65) | MEN1KMT2AL3MBTL1HRH3ALDH1A1 | |
| SCHEMBL18417689 | 0.83 | MEN1 (0.61) | MEN1KMT2AHRH3SMN1; SMN2KDM4E | |
| SCHEMBL18417679 | 0.83 | MEN1 (0.61) | MEN1KMT2AL3MBTL1HRH3SMN1; SMN2 | |
| SCHEMBL20579223 | 0.83 | MEN1 (0.64) | MEN1KMT2AL3MBTL1HRH3GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10351523-B2 | UV-absorbing compounds with at least one reactive hydrogen | ISP INVESTMENTS LLC | 2019-07-16 | — | — | US | disclosed |
| US-10351523-B2 | UV-absorbing compounds with at least one reactive hydrogen | ISP INVESTMENTS LLC | 2019-07-16 | — | — | US | disclosed |
| US-20180355242-A1 | OXYGEN SENSING DIFLUOROBORON B-DIKETONATE POLYLACTIDE MATERIALS FOR WOUND IMAGING | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2018-12-13 | — | — | US | disclosed |
| EP-3386991-A1 | POLYCYCLIC COMPOUNDS AS INHIBITORS OF BRUTON'S TYROSINE KINASE | Janssen Pharmaceutica NV (BE) | 2018-10-17 | — | — | EP | disclosed |
| US-20180099927-A1 | UV-ABSORBING COMPOUNDS WITH AT LEAST ONE REACTIVE HYDROGEN | ISP INVESTMENTS LLC (US) | 2018-04-12 | — | — | US | disclosed |
| US-20180099927-A1 | UV-ABSORBING COMPOUNDS WITH AT LEAST ONE REACTIVE HYDROGEN | ISP INVESTMENTS LLC (US) | 2018-04-12 | — | — | US | disclosed |
| US-20180099927-A1 | UV-ABSORBING COMPOUNDS WITH AT LEAST ONE REACTIVE HYDROGEN | ISP INVESTMENTS LLC (US) | 2018-04-12 | — | — | US | disclosed |
| WO-2017100662-A1 | POLYCYCLIC COMPOUNDS AS INHIBITORS OF BRUTON'S TYROSINE KINASE | JANSSEN PHARMACEUTICA NV (BE) | 2017-06-15 | — | — | WO | disclosed |
| WO-2017100764-A1 | OXYGEN SENSING DIFLUOROBORON B-DIKETONATE POLYLACTIDE MATERIALS FOR WOUND IMAGING | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2017-06-15 | — | — | WO | disclosed |
| US-20160002154-A1 | UV-ABSORBING COMPOUNDS WITH AT LEAST ONE REACTIVE HYDROGEN | ISP INVESTMENTS INC. (US) | 2016-01-07 | — | — | US | disclosed |
| US-20160002154-A1 | UV-ABSORBING COMPOUNDS WITH AT LEAST ONE REACTIVE HYDROGEN | ISP INVESTMENTS INC. (US) | 2016-01-07 | — | — | US | disclosed |
| US-20160002154-A1 | UV-ABSORBING COMPOUNDS WITH AT LEAST ONE REACTIVE HYDROGEN | ISP INVESTMENTS INC. (US) | 2016-01-07 | — | — | US | disclosed |
| WO-2014149363-A1 | UV-ABSORBING COMPOUNDS WITH AT LEAST ONE REACTIVE HYDROGEN | ISP INVESTMENTS INC. (US) | 2014-09-25 | — | — | WO | disclosed |
| US-7955861-B2 | Luminescent diketonate polymers | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2011-06-07 | — | — | US | disclosed |
| US-20090137057-A1 | LUMINESCENT DIKETONATE POLYMERS | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2009-05-28 | — | — | US | disclosed |
| WO-2007143209-A2 | LUMINESCENT DIKETONATE POLYMERS | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2007-12-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10351523-B2 | UV-absorbing compounds with at least one reactive hydrogen | ERCC1, ERCC4, UNG | MEN1 450/4885KMT2A 3448/4885L3MBTL1 4053/4885 |
| US-20160002154-A1 | UV-ABSORBING COMPOUNDS WITH AT LEAST ONE REACTIVE HYDROGEN | ERCC1, ERCC4, UNG | MEN1 450/4885KMT2A 3448/4885L3MBTL1 4053/4885 |
| US-20180099927-A1 | UV-ABSORBING COMPOUNDS WITH AT LEAST ONE REACTIVE HYDROGEN | ERCC1, ERCC4, UNG | MEN1 450/4885KMT2A 3448/4885L3MBTL1 4053/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.