⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19171552 | 0.65 | — | — | |
| SCHEMBL804643 | 0.59 | — | — | |
| SCHEMBL19865540 | 0.56 | — | — | |
| SCHEMBL23138777 | 0.56 | — | — | |
| SCHEMBL21449920 | 0.56 | — | — | |
| SCHEMBL24195 | 0.54 | — | — | |
| SCHEMBL685000 | 0.54 | — | — | |
| SCHEMBL172102 | 0.50 | — | — | |
| SCHEMBL18138387 | 0.47 | — | — | |
| SCHEMBL18608531 | 0.47 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021023609-A1 | COMBINATION OF A TYPE I PROTEIN ARGININE METHYLTRANSFERASE (TYPE I PRMT) INHIBITOR AND A METHIONINE ADENOSYLTRANSFERASE II ALPHA (MAT2A) INHIBITOR | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2021-02-11 | — | — | WO | disclosed |
| US-9752184-B2 | Methods for rapid forensic analysis of mitochondrial DNA and characterization of mitochondrial DNA heteroplasmy | IBIS BIOSCIENCES, INC. (US) | 2017-09-05 | — | — | US | disclosed |