Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 8/20 | 0.42 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.41 |
| ▸ | CETP | P11597 | 3/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26275584 | 1.00 | TLR2 (0.42) | TLR2PLA2G10PLA2G2ACETPPLA2G1B | |
| SCHEMBL17521646 | 1.00 | TLR2 (0.42) | TLR2PLA2G10PLA2G2ACETPPLA2G1B | |
| SCHEMBL19958189 | 1.00 | TLR2 (0.42) | TLR2PLA2G10PLA2G2ACETPPLA2G1B | |
| SCHEMBL18483905 | 0.90 | TDP1 (0.50) | PLA2G10PLA2G2APLA2G1BPLA2G5TDP1 | |
| SCHEMBL18484375 | 0.90 | TDP1 (0.50) | PLA2G10PLA2G2APLA2G1BPLA2G5TDP1 | |
| SCHEMBL18483904 | 0.90 | TDP1 (0.50) | PLA2G10PLA2G2APLA2G1BPLA2G5TDP1 | |
| SCHEMBL18641859 | 0.90 | PLA2G10 (0.47) | TLR2PLA2G10PLA2G2ACETPPLA2G1B | |
| SCHEMBL10604578 | 0.90 | PLA2G10 (0.47) | TLR2PLA2G10PLA2G2ACETPPLA2G1B | |
| SCHEMBL10605748 | 0.90 | PLA2G10 (0.47) | TLR2PLA2G10PLA2G2ACETPPLA2G1B | |
| SCHEMBL10604671 | 0.90 | PLA2G10 (0.47) | TLR2PLA2G10PLA2G2ACETPPLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170253628-A1 | PYRROLOPYRIMIDINE NUCLEOSIDES AND ANALOGS THEREOF | U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS COLLATERAL TRUSTEE | 2017-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170253628-A1 | PYRROLOPYRIMIDINE NUCLEOSIDES AND ANALOGS THEREOF | TYMP, PNP, DPYD | TLR2 2677/4885PLA2G10 629/4885PLA2G2A 216/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.