SCHEMBL1933175

SCHEMBL1933175

Cc1c(Cl)nc2c(C=O)cnn2c1N(C(=O)O)C1CC1

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CSNK2B P67870 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1487811 0.86 CSNK2B (0.35) CSNK2B
SCHEMBL1486067 0.72 CSNK2B (0.51) CSNK2B
SCHEMBL3198206 0.72 CSNK2B (0.37) CSNK2B
SCHEMBL14163278 0.71 CSNK2B (0.35) CSNK2B
SCHEMBL12587653 0.71 CSNK2B (0.39) CSNK2B
SCHEMBL19526985 0.69 CSNK2B (0.36) CSNK2B
SCHEMBL1487758 0.68 CSNK2B (0.37) CSNK2B
SCHEMBL1486089 0.66 CSNK2B (0.44) CSNK2B
SCHEMBL19527086 0.65 CSNK2B (0.43) CSNK2B
SCHEMBL14158115 0.65 CSNK2B (0.41) CSNK2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2509602-B1 PYRAZOLOPYRIMIDINES AND RELATED HETEROCYCLES AS CK2 INHIBITORS SENHWA BIOSCIENCES INC (TW) 2017-01-25 EP disclosed
WO-2012170827-A2 PYRAZOLOPYRIMIDINES AND RELATED HETEROCYCLES AS CK2 INHIBITORS CYLENE PHARMACEUTICALS, INC. (US) 2012-12-13 WO disclosed
EP-2509602-A1 PYRAZOLOPYRIMIDINES AND RELATED HETEROCYCLES AS CK2 INHIBITORS Cylene Pharmaceuticals, Inc. (US) 2012-10-17 EP disclosed
WO-2011068667-A1 PYRAZOLOPYRIMIDINES AND RELATED HETEROCYCLES AS CK2 INHIBITORS CYLENE PHARMACEUTICALS, INC. (US) 2011-06-09 WO disclosed