Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29699144 | 1.00 | HPGD (0.41) | HPGDUSP2SMN1; SMN2KDM1ARECQL | |
| Hydrochloric Acid SCHEMBL29699111 | 0.98 | HPGD (0.40) | HPGDUSP2SMN1; SMN2KDM1ARECQL | |
| SCHEMBL16044435 | 0.89 | HPGD (0.41) | HPGDUSP2SMN1; SMN2KDM1ARECQL | |
| SCHEMBL16042188 | 0.87 | HPGD (0.46) | HPGDUSP2SMN1; SMN2KDM1ARECQL | |
| SCHEMBL16042190 | 0.87 | HPGD (0.46) | HPGDUSP2SMN1; SMN2KDM1ARECQL | |
| SCHEMBL16042332 | 0.87 | HPGD (0.46) | HPGDUSP2SMN1; SMN2KDM1ARECQL | |
| SCHEMBL23826942 | 0.86 | HPGD (0.47) | HPGDUSP2SMN1; SMN2KDM1ARECQL | |
| SCHEMBL15769569 | 0.86 | HPGD (0.47) | HPGDUSP2SMN1; SMN2KDM1ARECQL | |
| SCHEMBL28622796 | 0.86 | HPGD (0.47) | HPGDUSP2SMN1; SMN2KDM1ARECQL | |
| Hydrochloric Acid SCHEMBL30803165 | 0.84 | HPGD (0.46) | HPGDUSP2SMN1; SMN2KDM1ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017156177-A1 | 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF | RAZE THERAPEUTICS, INC. (US) | 2017-09-14 | — | — | WO | disclosed |